TF Home
 
FAQ

No  Question
1  What is ITFP?
2  What method and material are used in ITFP to obtain TF and target pairs?
3  How do I cite ITFP?
 
1 What is ITFP?
    ITFP : Integrated Transcription Factor Platform. Currently, following transcription factor module are constructed. TFViewer : an online browse tool for transcription factor. TFMiner : an online prediction tool for transcription factor. TFSearcher : an online search tool for transcription factor.
 
2 What method and material are used in ITFP to obtain TF and target pairs?
    In our work, a reverse engineering method named ARACNE was used to derive potential interaction pairs between transcription factor and downstream regulated gene from Human gene expression profile data. Here, we collected gene expression profile data from Affymetrix human Genome U133 plus 2.0 Array platform in GEO database. Finally, gene expression profile dataset containing 302 (22 tissues) samples was built for Human. Here is datailed information of the dataset of Human.
 
3 How do I cite ITFP?
   
  • The combination approach of SVM and ECOC for powerful identification and classification of transcription factor, Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun Wei, Lu Xie, Yangyong Zhu and Yixue Li, BMC Bioinformatics 2008, 9:282.    
  • ITFP: an integrated platform of mammalian transcription factors, Guangyong Zheng, Kang Tu, Qing Yang, Yun Xiong, Chaochun Wei, Lu Xie, Yangyong Zhu, and Yixue Li, Bioinformatics 2008 24(20):2416-2417.
  •