Welcome to PhoSigNet!

PhoSigNet is a systematic resource for phosphorylation mediated signaling network, consisting of a background network database and two analysis tools. The PhoSigNet database incorporates the existing features of numerous previous databases, with an emphasis on collecting kinase-substrate relations and their up- or down- stream interactions.
Download All Data in PhoSigNet


  • network edge: 11,976

  • network node: 3,241

  • phosphorylation site: 216,871

  • dephosphorylation site: 258

  • more...


    Zhang M, et al. Construction and Deciphering of Human Phosphorylation-Mediated Signaling Transduction Networks . J Proteome Res. 2015 Jun 11.





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    PhoSigNet is currently developed and maintained by Menghuan Zhang and Lu Xie at SCBIT.
    @2015 Menghuan Zhang, Lu Xie